Tropomyosin antibody [SPM224]

GeneTex

Tropomyosin antibody [SPM224]

9

For IF: Use at an assay dependent dilution. For IHC-P: Use at a dilution of 1:50. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10 min followed by cooling at RT for 20 min. Optimal dilutions/concentrations should be determined by the researcher.

ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

SPM224

0.1 mg/ml

Unconjugated

Liquid

TPM1

tropomyosin 1

alpha tropomyosin of brain; alpha tropomyosin of fibroblasts F2; alpha-fTM; alpha-tropomyosin 1; alpha-tropomyosin 2; alpha-tropomyosin of skeletal fast muscle; tropomyosin (CTm4); tropomyosin (CTm7); tropomyosin 1 (alpha); tropomyosin alpha-1 chain; tropomyosin-1

Mouse

IgG1

Tropomyosin is a dimeric coiled-coil protein that binds along the length of actin filaments. It is associated with the thin filaments of muscle cells and the microfilaments of nonmuscle cells. Chicken embryo fibroblasts (CEF) contain five isoforms of tropomyosin (a, b, 1, 2, and 3), identified as such by their different apparent molecular masses after separation by SDS-PAGE, but similar biochemical properties, such as resistance to heat and organic solvents, the ability to bind to F-actin filaments, and the lack of proline and tryptophan.

Chicken, Human, Rat

2°C to 8°C

12352203