TRP1 / Tyrosinase-Related Protein-1 Antibody

Biorbyt

TRP1 / Tyrosinase-Related Protein-1 Antibody

16

The optimal dilution of the TRP1 antibody for each application should be determined by the researcher.

Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (Frozen): 1-2ug/ml for 30 min at RT FACS, IF, IHC-Fr

Research Use Only

Monoclonal

TA99

Unconjugated

TYRP1

tyrosinase related protein 1

5,6-dihydroxyindole-2-carboxylic acid oxidase; b-PROTEIN; CAS2; catalase B; CATB; DHICA oxidase; glycoprotein 75; GP75; melanoma antigen gp75; OCA3; TRP; TRP1; TYRP

Mouse

IgG2a

5,6-dihydroxyindole-2-carboxylic acid oxidase

It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Human, Mouse

-20°C,2°C to 8°C

12352203