TRP1 / Tyrosinase-Related Protein-1 Antibody

Biorbyt

TRP1 / Tyrosinase-Related Protein-1 Antibody

16

Titering of the TYRP1 antibody may be required for optimal performance.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

ELISA: 2-4ug/ml (order BSA/azide-free format),Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT ELISA, IHC-P

Research Use Only

Monoclonal

TYRP1/1986

Unconjugated

TYRP1

tyrosinase related protein 1

5,6-dihydroxyindole-2-carboxylic acid oxidase; b-PROTEIN; CAS2; catalase B; CATB; DHICA oxidase; glycoprotein 75; GP75; melanoma antigen gp75; OCA3; TRP; TRP1; TYRP

Mouse

IgG2b

5,6-dihydroxyindole-2-carboxylic acid oxidase

Tyrosinase-Related Protein-1/TYRP1/TRP1 is a melanocyte-specific gene product involved in melanin synthesis. While mouse Tyrp1 possesses dihydroxyindole carboxylic acid oxidase activity, the function in human melanocytes is less clear. In addition to its role in melanin synthesis, Tyrp1 is involved in stabilizing of tyrosinase protein and modulating its catalytic activity. Tyrp1 is also involved in maintenance of melanosome structure and affects melanocyte proliferation and melanocyte cell death. [Wiki]

Human

-20°C,2°C to 8°C

12352203