TRP1 / Tyrosinase-Related Protein-1 Antibody

Biorbyt

TRP1 / Tyrosinase-Related Protein-1 Antibody

16

Optimal dilution of the antibody should be determined by the researcher.

ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

ELISA (order BSA-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml ELISA, IHC-P

Research Use Only

Monoclonal

TYRP1/3284

Unconjugated

TYRP1

tyrosinase related protein 1

5,6-dihydroxyindole-2-carboxylic acid oxidase; b-PROTEIN; CAS2; catalase B; CATB; DHICA oxidase; glycoprotein 75; GP75; melanoma antigen gp75; OCA3; TRP; TRP1; TYRP

Mouse

IgG2b

5,6-dihydroxyindole-2-carboxylic acid oxidase

It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Human

-20°C,2°C to 8°C

12352203