TRPV1 antagonist 3

MedChem Express

TRPV1 antagonist 3

5

Research Use Only

99.3%

C23H25N3OS

391.53

TRPV1 antagonist 3 (Compound 7q) is a potent TRPV1 antagonist with an IC50 of 2.66 nM against capsaicin. TRPV1 antagonist 3 is mode-selective, oral bioavailable (F = 60%) and CNS-penetrant.

CC(C1=CC=CC(NC(N2CCC[C@H]2C3=NC=C(S3)C4=CC=CC=C4)=O)=C1)C

2°C to 8°C,-20°C,-80°C

12352200