TRPV1 antagonist 9
HY-110091
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameTRPV1 antagonist 9 [939040-79-6]
- Delivery Days Customer5
- CertificationResearch Use Only
- Scientific DescriptionTRPV1 antagonist 9 (compound 13c) is an orally active transient receptor potential vanilloid 1 ( TRPV1 ) channel antagonist. TRPV1 antagonist 9 blocks Ca 2+ uptake by CHO cells expressing TRPV1 receptors with IC 50 values are 0.6 and 0.8 nM for Capsaicin (HY-10448) and acid-induced Ca 2+ uptake, respectively. TRPV1 antagonist 9 blocks Capsaicin (HY-10448)-induced flinch response and causes hyperthermia in rats [1] .
- UNSPSC12352200