TrxR1-IN-B19

MedChem Express

TrxR1-IN-B19

5

Research Use Only

C21H22O5

354.40

TrxR1-IN-B19 (GO-Y015) (Compound B19) is a Curcumin (HY-N0005) derivative and colvalent TrxR1 inhibitor. TrxR1-IN-B19 inhibits TrxR1 enzyme activity to elevate oxidative stress, and then induce ROS-mediated ER Stress and mitochondrial dysfunction, subsequently resulting in cell cycle arrest and apoptosis [1] .

COC(C(OC)=CC=C1)=C1/C=C/C(/C=C/C2=C(C(OC)=CC=C2)OC)=O

12352200