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TSC1 antibody

Research Use Only
ORB106930
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetTSC1

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Overview

  • Supplier
    Biorbyt
  • Product Name
    TSC1 antibody
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB: 1:1000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Clone ID
    RB42204
  • Conjugate
    Unconjugated
  • Gene ID7248
  • Target name
    TSC1
  • Target description
    TSC complex subunit 1
  • Target synonyms
    hamartin; LAM; truncated hemartin; TSC; tuberous sclerosis 1 protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92574
  • Protein Name
    Hamartin
  • Scientific Description
    Rabbit polyclonal to TSC1. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
  • Reactivity
    Human
  • UNSPSC
    12352203