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TSC1 antibody, PAb

Research Use Only
ORB106930
Biorbyt
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
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More than 130 suppliers
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Overview

  • Supplier
    Biorbyt
  • Product Name
    TSC1 antibody, PAb
  • Delivery Days Customer
    10
  • Applications
    Western Blot, ELISA
  • Applications Supplier
    WB: 1:1000 ELISA, WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal to TSC1. In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
  • Reactivity
    Human
  • UNSPSC
    12352203