TT-012

MedChem Express

TT-012

14

Research Use Only

99.89

C19H15N3O4

349.34

TT-012 is a specifical inhibitor of MITF (microphthalmia transcription factor) and destroys the MITFs dimer formation and DNA-binding ability. TT-012 inhibits the transcriptional activity of MITF in B16F10 melanoma cells. TT-012 inhibits the growth of high-MITF melanoma cells, and inhibits the tumor growth and metastasis with tolerable toxicity to liver and immune cells in animal models [1] .

O=C(/C=C/C1=CC=CO1)NC2=CC=CC(NC(/C=C/C3=CC=CO3)=O)=N2

-20°C,2°C to 8°C

12352200