TTA-A8 [1146395-46-1]

MedChem Express

TTA-A8 [1146395-46-1]

5

1146395-46-1

Research Use Only

C22H21F3N4O2

430.42

TTA-A8 (Compound 13) is a short-acting T-type calcium channel antagonist with oral activity, exhibiting an IC50 value of 31.3 nM in the FLIPR depolarization assay. TTA-A8 possesses favorable pharmacokinetic properties, making it suitable for research on epilepsy and sleep[1].

CC1=NC=CN=C1C2=CC=C(C=C2)CC(N[C@@H](C3=CC=C(C=N3)OCC(F)(F)F)C)=O

12352200