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Tubacin [537049-40-4]

T8000
LKT Laboratories
Estimated Purity≥96%
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Product group Chemicals
€ 419,00
1 mg
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Overview

  • Supplier
    LKT Laboratories
  • Product Name
    Tubacin [537049-40-4]
  • Delivery Days Customer
    7
  • Estimated Purity
    ≥96%
  • Format
    DMSO 100 mg/mL (138.53 mM); Water Insoluble; Ethanol Insoluble
  • Scientific Description
    HDAC6 inhibitor.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Liu W, Fan LX, Zhou X, et al. HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells. PLoS One. 2012;7(11):e49418. d PMID: 23152903. Aldana-Masangkay GI, Rodriguez-Gonzalez A, Lin T, et al. Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells. Leuk Lymphoma. 2011 Aug;52(8):1544-55. PMID: 21699378. Hideshima T, Bradner JE, Wong J, et al. Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8567-72. PMID: 15937109. Haggarty SJ, Koeller KM, Wong JC, et al. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4389-94. PMID: 12677000.