Tubulin polymerization-IN-61 [2758114-60-0]

TargetMol Chemicals

Tubulin polymerization-IN-61 [2758114-60-0]

16

Research Use Only

C22H21N3O5

407.42

Tubulin polymerization-IN-61 (Compound 9a), a tubulin polymerization inhibitor, disrupts the microtubule skeleton, arrests the cell cycle at the G2/M phase, induces Apoptosis, and impedes cancer cell migration and colony formation. This compound demonstrates antitumor efficacy in vivo within the 4T1 xenograft model [1].

O(C)C=1C=C(N2C=3C(N=N2)=CC=C(C3)C4=CC(O)=C(OC)C=C4)C=C(OC)C1OC

-20°C

51202000