Tubulin polymerization-IN-69

MedChem Express

Tubulin polymerization-IN-69

9

Research Use Only

C25H21N7O5S

531.54

Tubulin polymerization-IN-69 (compund 6c) significantly inhibits microtubule/tubulin polymerization in vitro (78.3% inhibition) with an IC50 value of 6.53 microM, and rapidly induces apoptotic cell death and G2/M cell cycle arrest in MCF-7 cells[1].

O=C(C1=C2C=CC=C1)N(CC3=CN(CCC(NC4=CC=C(S(=O)(NC5=NC=CC=C5)=O)C=C4)=O)N=N3)C2=O

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