Tucatinib [937263-43-9]
S8362
CAS Number937263-43-9
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameTucatinib [937263-43-9]
- Delivery Days Customer9
- CAS Number937263-43-9
- CertificationResearch Use Only
- Scientific DescriptionTucatinib (Irbinitinib, ONT-380, ARRY-380) is an oral, potent, selective, reversible and ATP-competitive small-molecule inhibitor of ErbB-2 (also called HER2) with IC50s of 8 nM and 7 nM for ErbB-2 and p95 HER2, respectively in cell-based assays, showing ~500-fold selective for HER2 vs EGFR. It has potential antineoplastic activity.
- UNSPSC12352200
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