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Tucidinostat

Tucidinostat

T4481
TargetMol Chemicals
CAS Number1616493-44-7
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Product group Chemicals
Molecular Weight390.41
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Tucidinostat
  • Delivery Days Customer
    4
  • CAS Number
    1616493-44-7
  • Category Supplier
    Chemical
  • Chemical Name
    Tucidinostat
  • Molecular Formula
    C22H19FN4O2
  • Molecular Weight
    390.41
  • Scientific Description
    Tucidinostat (Chidamide) is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9.
  • Shelf life instruction
    3 years
  • SMILES
    C(NC1=C(N)C=C(F)C=C1)(=O)C2=CC=C(CNC(/C=C/C=3C=CC=NC3)=O)C=C2
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Ning ZQ, et al. Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity. Cancer Chemother Pharmacol. 2012 Apr;69(4):901-9.
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