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TUG-499

TUG-499

T60184
TargetMol Chemicals
CAS Number1206629-08-4
Product group Chemicals
Molecular Weight320.17
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Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TUG-499
  • Delivery Days Customer
    9
  • CAS Number
    1206629-08-4
  • Category Supplier
    Chemical
  • Chemical Name
    TUG-499
  • Molecular Formula
    C16H11Cl2NO2
  • Molecular Weight
    320.17
  • Scientific Description
    TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39).TUG-499 has an affinity for FFAR1 or GPR40 over the related receptors FFA2, FFA3 and the nuclear receptor PPARgamma, as well as other different receptors, ion channels and transporter proteins.TUG-499 can be used to study type 2 Type 2 diabetes.
  • Shelf life instruction
    3 years
  • SMILES
    C(#CC1=CC=C(CCC(O)=O)C=C1)C=2C=C(Cl)N=C(Cl)C2
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Christiansen E, et al. Identification of a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with favorable physicochemical and in vitro ADME properties. J Med Chem. 2011;54(19):6691-6703.
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