TY-011

MedChem Express

TY-011

9

Research Use Only

C18H16ClN5

337.81

TY-011 is an Aurora A/B kinase inhibitor. TY-011 induces abnormal microtubule-kinetochore attachment, leading to DNA damage and apoptosis ( Apoptosis ) in human gastric cancer cells, and ultimately inhibits cancer cell proliferation, with an IC 50 value ranging from 0.11 to 4.49 microM in human gastric cancer cell lines. TY-011 has potential applications in gastric cancer research [1] .

CC1=C(C(N2)=NN1)N=C(C3=CC=CC=C3Cl)C4=C2C=C(CC)N=C4

12352200