Tyk2-IN-16 [3010874-30-0]

TargetMol Chemicals

Tyk2-IN-16 [3010874-30-0]

16

Research Use Only

C20H20F2N8O

426.42

Tyk2-IN-16 is a potent and selective TYK2 inhibitor with an IC50 of less than 10 nM for TYK2-JH2. It inhibits pSTAT4 in NK92 cells with an IC50 of under 10 nM (WO2023220046A1; compound 184) [1].

N(C(C)=O)C=1C=C2C(C(=NN2C=3N=C(C(C)(F)F)C=CN3)N4CC(C#N)(C)CC4)=CN1

-20°C

51202000