Tyk2-IN-22

MedChem Express

Tyk2-IN-22 [933667-23-3]

5

Research Use Only

C16H16ClN5O2

345.78

Tyk2-IN-22 (Compound A8) is a selective inhibitor for tyrosine kinase 2 (Tyk2), that it inhibits Tyk2, JAK1, and JAK3 with IC50s of 9.7, 148.6, and 883.3 nM, respectively. Tyk2-IN-22 inhibits the downstream STAT5 phosphorylation[1].

O=C1N2C(NC(C3=CC=C(Cl)C=C3)=N2)=NC(CN4CCOCC4)=C1

12131703