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Tz-Thalidomide

HY-101460
MedChem Express
Estimated Purity98.01
Product group Chemicals
Molecular Weight571.58
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tz-Thalidomide
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Estimated Purity
    98.01
  • Molecular Formula
    C29H29N7O6
  • Molecular Weight
    571.58
  • Scientific Description
    Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) ( Ligands for E3 Ligase ). Tz-Thalidomide has binding affinity for BRD4 , with IC 50 s of 46.25 microM (BRD4-1) and 62.55 microM (BRD4-2). Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups [1] .
  • SMILES
    O=C(CCCCCOC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1)NCC(C=C4)=CC=C4C5=NN=C(C)N=N5
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200