UAWJ9-36-1

TargetMol Chemicals

UAWJ9-36-1

107

2663837-73-6

Chemical

UAWJ9-36-1

C23H29N3O5

427.49

UAWJ9-36-1 is a SARS-CoV-2 Protease inhibitor (IC50 = 51 nM). UAWJ9-36-1 showed potent binding and enzymatic inhibition against the Mpro's from SARS-CoV-2, SARS-CoV, MERS-CoV, HCoV-OC43, HCoV-NL63, HCoV-229E, and HCoV-HKU1. UAWJ9-36-1 is a promising candidate to be further developed as a broad-spectrum coronavirus antiviral.

3 years

C(N[C@@H](C[C@H]1C(=O)NCC1)C=O)(=O)C2[C@@]3([C@](CN2C(OCC4=CC=CC=C4)=O)(CCC3)[H])[H]

-20°

12352200