
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA179850(UBB Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200)
UBB Antibody
CSB-PA179850
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetUBB
Overview
- SupplierCusabio
- Product NameUBB Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7314
- Target nameUBB
- Target descriptionubiquitin B
- Target synonymsepididymis secretory protein Li 50; HEL-S-50; polyubiquitin B; polyubiquitin-B
- HostRabbit
- IsotypeIgG
- Protein IDP0CG47
- Protein NamePolyubiquitin-B
- Scientific DescriptionThis gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimers disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203