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ProductsBack/UBE2B antibody

UBE2B antibody

GTX100416
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetUBE2B
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Overview

  • Supplier
    GeneTex
  • Product Name
    UBE2B antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    2.72 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7320
  • Target name
    UBE2B
  • Target description
    ubiquitin conjugating enzyme E2 B
  • Target synonyms
    E2 protein; E2 ubiquitin-conjugating enzyme B; E2-17kDa; HHR6B; HR6B; RAD6 homolog B; RAD6B; UBC2; ubiquitin carrier protein B; ubiquitin conjugating enzyme E2B; ubiquitin-conjugating enzyme E2 B; ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2B (RAD6 homolog); ubiquitin-protein ligase B
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP63146
  • Protein Name
    Ubiquitin-conjugating enzyme E2 B
  • Scientific Description
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Role of high ubiquitin-conjugating enzyme E2 expression as a prognostic factor in nasopharyngeal carcinoma. Kao WC et al., 2022 Jun, Oncol Lett
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  • Ubiquitin-conjugating enzyme E2 B regulates the ubiquitination of O6-methylguanine-DNA methyltransferase and BCNU sensitivity in human nasopharyngeal carcinoma cells. Hsu SH et al., 2018 Dec, Biochem Pharmacol
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  • Up-regulation of miR-455-5p by the TGF-beta-SMAD signalling axis promotes the proliferation of oral squamous cancer cells by targeting UBE2B. Cheng CM et al., 2016 Sep, J Pathol
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