UBE2B antibody
GTX100416
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetUBE2B
Overview
- SupplierGeneTex
- Product NameUBE2B antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration2.72 mg/ml
- ConjugateUnconjugated
- Gene ID7320
- Target nameUBE2B
- Target descriptionubiquitin conjugating enzyme E2 B
- Target synonymsE2-17kDa, HHR6B, HR6B, RAD6B, UBC2, ubiquitin-conjugating enzyme E2 B, E2 protein, E2 ubiquitin-conjugating enzyme B, RAD6 homolog B, ubiquitin carrier protein B, ubiquitin conjugating enzyme E2B, ubiquitin-conjugating enzyme E2-17 kDa, ubiquitin-conjugating enzyme E2B (RAD6 homolog), ubiquitin-protein ligase B
- HostRabbit
- IsotypeIgG
- Protein IDP63146
- Protein NameUbiquitin-conjugating enzyme E2 B
- Scientific DescriptionThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Kao WC, Hsu SH, Lin CL, et al. Role of high ubiquitin-conjugating enzyme E2 expression as a prognostic factor in nasopharyngeal carcinoma. Oncol Lett. 2022,23(6):194. doi: 10.3892/ol.2022.13314Read this paper
- Hsu SH, Chen SH, Kuo CC, et al. Ubiquitin-conjugating enzyme E2 B regulates the ubiquitination of O(6)-methylguanine-DNA methyltransferase and BCNU sensitivity in human nasopharyngeal carcinoma cells. Biochem Pharmacol. 2018,158:327-338. doi: 10.1016/j.bcp.2018.10.029Read this paper
- Cheng CM, Shiah SG, Huang CC, et al. Up-regulation of miR-455-5p by the TGF-β-SMAD signalling axis promotes the proliferation of oral squamous cancer cells by targeting UBE2B. J Pathol. 2016,240(1):38-49. doi: 10.1002/path.4752Read this paper
Datasheet
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