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Western blot analysis of extracts from HeLa cells, A549 cells and K562 cells, using UBE2D2 antibody.
Western blot analysis of extracts from HeLa cells, A549 cells and K562 cells, using UBE2D2 antibody.
Western blot analysis of extracts from HeLa cells, A549 cells and K562 cells, using UBE2D2 antibody.

UBE2D2 Antibody

CSB-PA826958
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetUBE2D2
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Overview

  • Supplier
    Cusabio
  • Product Name
    UBE2D2 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID7322
  • Target name
    UBE2D2
  • Target description
    ubiquitin conjugating enzyme E2 D2
  • Target synonyms
    (E3-independent) E2 ubiquitin-conjugating enzyme D2; E2 ubiquitin-conjugating enzyme D2; E2(17)KB2; p53-regulated ubiquitin-conjugating enzyme 1; PUBC1; UBC4; UBC4/5; UBCH4; UBCH5B; ubiquitin carrier protein D2; ubiquitin conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2 D2; ubiquitin-conjugating enzyme E2-17 kDa 2; ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); ubiquitin-protein ligase D2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP62837
  • Protein Name
    Ubiquitin-conjugating enzyme E2 D2
  • Scientific Description
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes Lys-48-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3. Jensen J.P., J. Biol. Chem. 270:30408-30414(1995). Rolfe M., Proc. Natl. Acad. Sci. U.S.A. 92:3264-3268(1995). Guinn B.-A., Biochem. Biophys. Res. Commun. 335:1293-1304(2005).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203