UBE2D2 Antibody, HRP conjugated

Cusabio

UBE2D2 Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

UBE2D2

ubiquitin conjugating enzyme E2 D2

(E3-independent) E2 ubiquitin-conjugating enzyme D2; E2 ubiquitin-conjugating enzyme D2; E2(17)KB2; p53-regulated ubiquitin-conjugating enzyme 1; PUBC1; UBC4; UBC4/5; UBCH4; UBCH5B; ubiquitin carrier protein D2; ubiquitin conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2 D2; ubiquitin-conjugating enzyme E2-17 kDa 2; ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); ubiquitin-protein ligase D2

Rabbit

IgG

Ubiquitin-conjugating enzyme E2 D2

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes \Lys-48\-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.

Human

-20°C or -80°C

12352203