UBE4B Polyclonal Antibody

Reddot Biotech

UBE4B Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

UBE4B

ubiquitination factor E4B

E4; HDNB1; homologous to yeast UFD2; homozygously deleted in neuroblastoma-1; RING-type E3 ubiquitin transferase E4 B; ubiquitin conjugation factor E4 B; ubiquitination factor E4B (UFD2 homolog, yeast); ubiquitin-fusion degradation protein 2; UBOX3; UFD2; UFD2A

Rabbit

IgG

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Human, Mouse

-20°C

12352203