UGT1A4 antibody
GTX32949
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetUGT1A4
Overview
- SupplierGeneTex
- Product NameUGT1A4 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID54657
- Target nameUGT1A4
- Target descriptionUDP glucuronosyltransferase family 1 member A4
- Target synonymsGNT1, HUG-BR2, UDPGT, UDPGT 1-4, UGT-1A, UGT-1D, UGT1, UGT1-01, UGT1-04, UGT1.1, UGT1.4, UGT1A, UGT1A1, UGT1A4S, UGT1D, hUG-BR1, UDP-glucuronosyltransferase 1A4, Bilirubin-specific UDPGT isozyme 1, UDP glucuronosyltransferase 1 family, polypeptide A4, UDP glycosyltransferase 1 family, polypeptide A4, UDP-glucuronosyltransferase 1 family polypeptide A4s, UDP-glucuronosyltransferase 1-1, UDP-glucuronosyltransferase 1-4, UDP-glucuronosyltransferase 1-A, UDP-glucuronosyltransferase 1-D, UDP-glucuronosyltransferase 1A1, UDPGT 1-1, bilirubin UDP-glucuronosyltransferase isozyme 2, bilirubin-specific UDPGT isozyme 2
- HostRabbit
- IsotypeIgG
- Protein IDP22310
- Protein NameUDP-glucuronosyltransferase 1A4
- Scientific DescriptionThis gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5 exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203


