UGT1A4 Polyclonal Antibody

Reddot Biotech

UGT1A4 Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

UGT1A4

UDP glucuronosyltransferase family 1 member A4

bilirubin UDP-glucuronosyltransferase isozyme 2; Bilirubin-specific UDPGT isozyme 1; bilirubin-specific UDPGT isozyme 2; GNT1; hUG-BR1; HUG-BR2; UDP glucuronosyltransferase 1 family, polypeptide A4; UDP glycosyltransferase 1 family, polypeptide A4; UDP-glucuronosyltransferase 1 family polypeptide A4s; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1-4; UDP-glucuronosyltransferase 1-A; UDP-glucuronosyltransferase 1A1; UDP-glucuronosyltransferase 1A4; UDP-glucuronosyltransferase 1-D; UDPGT; UDPGT 1-1; UDPGT 1-4; UGT1; UGT1.1; UGT1.4; UGT1-01; UGT1-04; UGT1A; UGT-1A; UGT1A1; UGT1A4S; UGT1D; UGT-1D

Rabbit

IgG

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5 exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.

Human, Mouse

-20°C

12352203