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IHC-P analysis of human prostate carcinoma using GTX81884 UGT2B17 antibody, Internal.
IHC-P analysis of human prostate carcinoma using GTX81884 UGT2B17 antibody, Internal.
IHC-P analysis of human prostate carcinoma using GTX81884 UGT2B17 antibody, Internal.

UGT2B17 antibody, Internal

GTX81884
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetUGT2B17
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Overview

  • Supplier
    GeneTex
  • Product Name
    UGT2B17 antibody, Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. IHC-P: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID7367
  • Target name
    UGT2B17
  • Target description
    UDP glucuronosyltransferase family 2 member B17
  • Target synonyms
    BMND12; C19-steroid-specific UDP-glucuronosyltransferase; C19-steroid-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B17; UDP glycosyltransferase 2 family, member B17; UDP-glucuronosyltransferase 2B17; UDP-glucuronyltransferase, family 2, beta-17; UDPGT2B17
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75795
  • Protein Name
    UDP-glucuronosyltransferase 2B17
  • Scientific Description
    This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.[provided by RefSeq, Apr 2010]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer. Zimmer BM et al., 2021 Sep 14, Oncotarget
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  • Trans-acting non-synonymous variant of FOXA1 predisposes to hepatocellular carcinoma through modulating FOXA1-ERalpha transcriptional program and may have undergone natural selection. Wang S et al., 2020 Apr 22, Carcinogenesis
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  • Pulmonary expression of CYP2A13 and ABCB1 is regulated by FOXA2, and their genetic interaction is associated with lung cancer. Xiang C et al., 2015 May, FASEB J
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