Uhrf2 Polyclonal Antibody

Reddot Biotech

Uhrf2 Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

Uhrf2

ubiquitin-like, containing PHD and RING finger domains 2

2310065A22Rik; AI426270; AW214556; D130071B19Rik; E3 ubiquitin-protein ligase UHRF2; N; Nirf; Np95-like ring finger protein; nuclear protein 97; nuclear zinc finger protein Np97; RING-type E3 ubiquitin transferase UHRF2; ubiquitin-like PHD and RING finger domain-containing protein 2; ubiquitin-like-containing PHD and RING finger domains protein 2

Rabbit

IgG

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.

Mouse, Rat

-20°C

12352203