Ulefnersen

MedChem Express

Ulefnersen

10

Research Use Only

Ulefnersen (ION363) is an Antisense Oligonucleotide ( ASO ) directed against the 6th intron of the fused-in sarcoma ( FUS ) transcript to silence FUS in a non-allele-specific manner. Ulefnersen can reduce postnatal levels of FUS protein in the brain and spinal cord in disease-relevant mouse model of ALS-FUS , delaying motor neuron degeneration. Ulefnersen can be used in the research of Amyotrophic Lateral Sclerosis (ALS) [1] .

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