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Umbralisib

HY-12279
MedChem Express
CAS Number1532533-67-7
DownloadMSDS
Product group Chemicals
Estimated Purity98.94
Molecular Weight571.55
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Umbralisib [1532533-67-7]
  • Delivery Days Customer
    10
  • CAS Number
    1532533-67-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.94
  • Molecular Formula
    C31H24F3N5O3
  • Molecular Weight
    571.55
  • Scientific Description
    Umbralisib (TGR-1202) is an orally active, potent and selective dual PI3Kdelta and casein kinase-1-epsilon (CK1epsilon) inhibitor, with EC50 of 22.2 nM and 6.0 microM, respectively. Umbralisib exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib can be used for haematological malignancies reseach[1][2][3][4].
  • SMILES
    O=C1C(C2=CC=CC(F)=C2)=C([C@@H](N3N=C(C4=CC=C(OC(C)C)C(F)=C4)C5=C(N)N=CN=C53)C)OC6=CC=C(F)C=C16
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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