UMPS Polyclonal Antibody

Reddot Biotech

UMPS Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.7 mg/ml

Unconjugated

UMPS

uridine monophosphate synthetase

OMPdecase; OPRT; OPRTase; orotate phosphoribosyltransferase; orotidine 5'-phosphate decarboxylase; UMP synthase; uridine 5'-monophosphate synthase

Rabbit

IgG

This gene encodes a uridine 5-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Human, Mouse

-20°C

12352203