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UNC0638 (hydrate)

HY-110093
MedChem Express
CAS Number1255517-77-1
Product group Chemicals
Molecular Weight527.74
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Overview

  • Supplier
    MedChem Express
  • Product Name
    UNC0638 (hydrate) [1255517-77-1]
  • Delivery Days Customer
    9
  • CAS Number
    1255517-77-1
  • Certification
    Research Use Only
  • Molecular Formula
    C30H49N5O3
  • Molecular Weight
    527.74
  • Scientific Description
    UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC 50 of 15 nM and 19 nM, respectively. UNC0638 hydrate inhibits TNBC cell invasion and migration in vitro. UNC0638 hydrate is also an inhibitor of EHMT1/2 and induces fetal hemoglobin ( HbF ) expression in human erythroid progenitor cell culture. In addition, UNC0638 hydrate has anti- FMDV (foot-and-mouth disease virus) and anti- VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets [1] [2] [3] [4] [5] .
  • SMILES
    CC(N1CCC(NC2=C3C=C(OC)C(OCCCN4CCCC4)=CC3=NC(C5CCCCC5)=N2)CC1)C.O
  • UNSPSC
    12352200