UNC0642 --- G9a/GLP HMTase Inhibitor
BS-60185C
Estimated Purity98.0
Product group Chemicals
Overview
- SupplierBioss
- Product NameUNC0642 --- G9a/GLP HMTase Inhibitor [1481677-78-4]
- Delivery Days Customer16
- CertificationResearch Use Only
- Estimated Purity98.0
- Scientific DescriptionUNC0642 is a novel highly potent, selective and cell permeable inhibitor of the homologous protein lysine methyltransferases, G9a and GLP, with IC50 1000-fold over 13 other HMTs and selected representatives of kinases, ion channels, 7TMs, and other epigenetic proteins. UNC0642 reduces H3K9 dimethylation levels in MDA-MB-231 cells (IC50~110 nM). It has improved PK properties relative to UNC0638 and displayed modest brain penetration in vivo.
- Storage Instruction-20°C
- UNSPSC51202000