UNC13B Polyclonal Antibody
RD218509A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetUNC13B
Overview
- SupplierReddot Biotech
- Product NameUNC13B Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.6 mg/ml
- ConjugateUnconjugated
- Gene ID10497
- Target nameUNC13B
- Target descriptionunc-13 homolog B
- Target synonymshomolog of rat Munc13 (diacylglycerol-binding); MUNC13; munc13-2; protein unc-13 homolog B; UNC13; Unc13h2; unc-13-like
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203