UNC2399 [2412791-72-9]
T40038
Overview
- SupplierTargetMol Chemicals
- Product NameUNC2399 [2412791-72-9]
- Delivery Days Customer999
- CAS Number2412791-72-9
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameUNC2399
- Molecular FormulaC67H104N10O17S
- Molecular Weight1353.68
- Scientific DescriptionUNC2399, a biotinylated version of UNC1999, functions as a selective degrader of EZH2 and exhibits strong in vitro efficacy against EZH2, demonstrated by its IC 50 value of 17 nM.
- Shelf life instruction3 years
- SMILES[H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)N3CCN(CC3)c3ccc(cn3)-c3cc(C(=O)NCc4c(CCC)cc(C)[nH]c4=O)c4cnn(C(C)C)c4c3)[C@@]1([H])NC(=O)N2
- Storage Instruction-20°C
- UNSPSC12352200
References
- Discovery of a first-in-class EZH2 selective degrader. Ma A et al., 2020 Feb, Nat Chem BiolRead more
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