UNC45B Polyclonal Antibody

Reddot Biotech

UNC45B Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.9 mg/ml

Unconjugated

UNC45B

unc-45 myosin chaperone B

cardiomyopathy associated 4; CMYA4; CTRCT43; MFM11; protein unc-45 homolog B; SMUNC45; striated muscle UNC45; UNC45; unc-45 homolog B; UNC-45B

Rabbit

IgG

This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants.

Human, Mouse

-20°C

12352203