UNC4976 (TFA)

MedChem Express

UNC4976 (TFA)

10

Research Use Only

98.0

C49H71F3N6O10

961.12

UNC4976 TFA is a positive allosteric modulator (PAM) peptidomimetic of CBX7 chromodomain binding to nucleic acids. UNC4976 TFA simultaneously antagonizes H3K27me3-specific recruitment of CBX7 to target genes while increasing non-specific binding to DNA and RNA [1] .

COC([C@H](CO)NC([C@H](CCCCN(C)C1C2CCC(C2)C1)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC3=CC=CC=C3)NC(C4=CC=C(C(C)(C)C)C=C4)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

-20°C,-80°C

12352200