Uridine-5-O-(3-thiotriphosphate) sodium

TargetMol Chemicals

Uridine-5-O-(3-thiotriphosphate) sodium

999

Chemical

Research Use Only

Uridine-5'-O-(3-thiotriphosphate) sodium

C9H11N2O14P3S.4Na

588.14

Uridine-5-O-(3-thiotriphosphate) (UTP-gamma-S) is a hydrolysis-resistant UTP derivative and an agonist of the purinergic P2Y2 receptor. It effectively induces inositol phosphate formation in 1321N1 astrocytoma cells harboring the human P2Y2 receptor (EC50 = 240 nM) and stimulates chloride secretion in a dose-dependent manner in primary nasal epithelial cells from cystic fibrosis patients. Moreover, UTP-gamma-S prompts vasoconstriction in isolated human coronary arteries (EC50 = 25.1 microM).

3 years

[S-]P([O-])(OP([O-])(OP([O-])(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)N2C=CC(NC2=O)=O)=O)=O)=O.[Na+].[Na+].[Na+].[Na+]

-20°C

12352200