Uroplakin 1A Antibody / UPK1A

Biorbyt

Uroplakin 1A Antibody / UPK1A

16

Optimal dilution of the antibody should be determined by the researcher.

ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

ELISA (order BSA-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml ELISA, IHC-P

Research Use Only

Monoclonal

UPK1A/2925

Unconjugated

UPK1A

uroplakin 1A

tetraspanin-21; TSPAN21; tspan-21; UP1A; UPIA; UPKA; uroplakin Ia; uroplakin-1a

Mouse

IgG1

Uroplakin-1a

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.

Human

-20°C,2°C to 8°C

12352203