USP12 Polyclonal Antibody
RD252445A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetUSP12
Overview
- SupplierReddot Biotech
- Product NameUSP12 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID219333
- Target nameUSP12
- Target descriptionubiquitin specific peptidase 12
- Target synonymsdeubiquitinating enzyme 12; UBH1; ubiquitin carboxyl-terminal hydrolase 12; ubiquitin specific protease 12 like 1; ubiquitin thioesterase 12; ubiquitin thiolesterase 12; ubiquitin-hydrolyzing enzyme 1; ubiquitin-specific-processing protease 12; USP12L1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP12 (ubiquitin specific peptidase 12), also known as UBH1 or USP12L1, is a 370 amino acid protein belonging to the peptidase C19 family and the USP12/USP46 subfamily. Considered a deubiquitinating enzyme, it is suggested that USP12 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have high activity. The gene encoding USP12 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203