USP28-IN-2
T74792
Overview
- SupplierTargetMol Chemicals
- Product NameUSP28-IN-2
- Delivery Days Customer65
- CAS Number2931509-11-2
- Category SupplierChemical
- Chemical NameUSP28-IN-2
- Molecular FormulaC23H20Cl2N2O3S
- Molecular Weight475.39
- Scientific DescriptionUSP28-IN-2 is a selective USP28 inhibitor (IC50 = 0.3 uM), demonstrating high specificity compared to USP2, USP7, USP8, USP9x, UCHL3, and UCHL5. This compound exhibits cytotoxic effects on cancer cells and induces the degradation of c-Myc via the ubiquitin-proteasome pathway. Additionally, USP28-IN-2 reduces ankyrin-1/2 levels in vitro and potentiates the responsiveness of colorectal cancer cells to Regorafenib [1].
- Shelf life instruction3 years
- SMILES#Reference to error in column [smiles]
- Storage Instruction-20°
- UNSPSC12352200