USP28-IN-4
T74794
CAS Number2931509-15-6
Product group Chemicals
Molecular Weight461.36
Overview
- SupplierTargetMol Chemicals
- Product NameUSP28-IN-4
- Delivery Days Customer65
- CAS Number2931509-15-6
- Category SupplierChemical
- Chemical NameUSP28-IN-4
- Molecular FormulaC22H18Cl2N2O3S
- Molecular Weight461.36
- Scientific DescriptionUSP28-IN-4 is a selective USP28 inhibitor (IC50 = 0.04 uM), demonstrating high specificity compared to USP2, USP7, USP8, USP9x, UCHL3, and UCHL5. It exhibits cytotoxic effects on cancer cells by inducing c-Myc degradation via the ubiquitin-proteasome pathway and reduces in vitro levels of ankyrin-1/2. Furthermore, USP28-IN-4 sensitizes colorectal cancer cells to Regorafenib [1].
- Shelf life instruction3 years
- SMILES#Reference to error in column [smiles]
- Storage Instruction-20°
- UNSPSC12352200