USP7-797

MedChem Express

USP7-797

10

Research Use Only

97.53

C27H28ClN3O3S

510.05

USP7-797 (USP7-IN-7) is an orally available, selective USP7 inhibitor ( IC 50 =0.5 nmol/L) with antitumor activity. USP7-797 reduces the level of MDM2 , thereby increasing the stability and activity of p53 , leading to cell cycle arrest and apoptosis . USP7-797 has low nanomolar cytotoxicity against p53 mutant cancer cell lines, p53 wild-type hematological tumors, and neuroblastoma cell lines [1] [2] .

O=C(N1CC2=CC3=NC=CC(C4=CC(Cl)=CC(C)=C4C[C@@H]5CNCCO5)=C3S2)C6C(C)(C)C6C1=O

2°C to 8°C

12352200