USP7-IN-9

MedChem Express

USP7-IN-9

10

Research Use Only

98.10

C32H33ClF6N6O8

779.08

USP7-IN-9 is a highly potent ubiquitin-specific protease 7 (USP7) inhibitor with an IC 50 value of 40.8 nM. USP7-IN-9 can induce apoptosis and arrest cell progression at G0/G1 and S phases in RS4; 11 cells. USP7-IN-9 reduces the protein levels of oncoproteins MDM2 and DNMT1 and increases the protein levels of tumor suppressors p53 and p21 [1] .

OC1(CN(C=NC2=C(C3=CC=C(C[NH3+])C=C3)N(C)N=C24)C4=O)CC[NH+](CC5=CC=C(C(OC)=O)C=C5Cl)CC1.O=C([O-])C(F)(F)F.O=C([O-])C(F)(F)F

2°C to 8°C

12352200