UVRAG Polyclonal Antibody

Reddot Biotech

UVRAG Polyclonal Antibody

5

ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

UVRAG

UV radiation resistance associated

beclin 1 binding protein; DHTX; disrupted in heterotaxy; p63; UV radiation resistance-associated gene protein; VPS38

Rabbit

IgG

This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.

Human, Mouse, Rat

-20°C

12352203