Val-Cit-PAB-Exatecan [2227350-99-2]

TargetMol Chemicals

Val-Cit-PAB-Exatecan [2227350-99-2]

16

Research Use Only

C43H49FN8O9

840.9

Val-Cit-PAB-Exatecan (Val-Cit-PAB-DX8951) serves as a conjugate of an agent-linker for antibody-drug conjugates (ADC). This compound consists of the DNA topoisomerase I inhibitor DX-8951 and a cathepsin-cleavable ADC linker [1].

N(C(OCC1=CC=C(NC([C@@H](NC([C@H](C(C)C)N)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7

-20°C

12352200