VAMP2 antibody [3E5]

GeneTex

VAMP2 antibody [3E5]

9

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 3,000. Recommended starting dilution is 1:2,000.

Western Blot, ELISA

Research Use Only

Monoclonal

1 mg/ml

Unconjugated

VAMP2

vesicle associated membrane protein 2

NEDHAHM; SYB2; synaptobrevin 2; VAMP-2; vesicle-associated membrane protein 2

Mouse

IgG1

Vesicle-associated membrane protein 2

The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008]

Human, Rat

-20°C or -80°C,2°C to 8°C

12352203